About TandemAI

TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution. We provide a cloud-based, all-in-one platform for medicinal and computational chemists in biotech and pharmaceutical companies, supporting every drug discovery stage from hit-finding to the synthesis and optimization of drug candidates.

ABOUT THE ROLE

TandemAI is seeking an experienced Senior Backend Engineer to join our growing Web Applications team. In this role, you will be responsible for designing, developing, and maintaining robust, scalable, and high-performance backend systems powering our easy-to-use web-based computational platform. The candidate, experienced in building scientific web applications, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates TandemAI’s physics-based computational drug discovery platform.

You will:

• Contribute to the development and maintenance of our backend, utilizing Java Spring Boot, PostgreSQL, OpenSearch, and Python.
• Collaborate with stakeholders and a global, multidisciplinary team to develop and maintain clean, robust code for a leading computational drug discovery platform, with cross-time-zone cooperation as a key pillar
• Discuss and make technical design and architecture decisions utilizing tools like UML for clear and consistent design across teams.
• Review code developed by team members and provide feedback to ensure best practices.
• Ensure long-term maintainability and consistent performance of deployed software through the creation and upkeep of automated tests.
• Design and deploy scalable systems across multiple environments, both on-premise and cloud
• Develop and optimize database schemas, queries, and data pipelines to handle large volumes of data efficiently.
• Identify and resolve performance bottlenecks, bugs, and other technical issues across the backend systems.

Qualifications:

• Bachelor’s degree or equivalent in Computer Science, Computational Chemistry, or related quantitative fields with 3-5+ years of professional web development experience.
• Demonstrated track record of developing scientific web applications using Java (a plus if you’ve worked with Java Spring Boot) \Extensive experience with database technologies, (e.g., PostgreSQL, OpenSearch).
• Experience with REST API design and service layer architecture.
• Experience with virtual private cloud deployments and multi-environment system architecture.
• Experience with Cheminformatics or knowledge of Chemistry a plus
• Familiarity with job scheduling using SLURM is a plus.
• Experience with computer-aided drug design and physics-based simulation is a plus, but not required.

Soft Skills

• Strong problem-solving skills and the ability to think critically.
• Excellent communication and collaboration skills
• Ability to work in a fast-paced, innovative environment with minimal supervision.
• Passion for biotechnology and a commitment to advancing scientific research.
• Experience with bioinformatics tools and platforms preferred.
• Knowledge of regulatory requirements in the biotech industry (e.g., HIPAA, GDPR) preferred.
• Experience with machine learning and AI integration in backend systems preferred.

Benefits:

• Medical, dental, vision and life insurance
• Unlimited Time Off
• Hybrid work schedule: Must be able to travel to NYC or Boston twice a week.

COMPENSATION

• Salary Range in NY/MA: $120,000 - $180,000